医学
急性肾损伤
发病机制
弥漫性肺泡损伤
肾脏替代疗法
肾脏疾病
肾病
肾移植
冠状病毒
肾
疾病
病理
免疫学
2019年冠状病毒病(COVID-19)
肺
重症监护医学
内科学
传染病(医学专业)
糖尿病
内分泌学
急性呼吸窘迫
作者
Lirong Lin,Junhui Deng,Wei Tan,Jie Li,Zhifeng Wu,Luquan Zheng,Jurong Yang
摘要
Coronavirus disease 2019 (COVID-19) can cause damage to multiple organ, not only to the lungs, but also to the kidneys. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute and chronic kidney disease through direct viral infection, indirect injury, and vaccination-related injury. Like lung injury, kidney injury is also an important aspect affecting the severity and prognosis of SARS-CoV-2. This article summarizes the pathogenesis, pathological manifestations, and clinical features of SARS-CoV-2 direct or indirect renal injury. Including direct injury, indirect injury, special comorbidities (receiving kidney transplantation and chronic kidney disease), and vaccine-related renal injury, and exploring the possible therapeutic effect of anti-SARS-CoV-2 therapy on renal injury. The purpose is to provide reference for understanding COVID-19-related renal injury, guiding clinical and pathological diagnosis and treatment, and evaluating prognosis.
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