Artificial intelligence (AI), including computer-aided detection (CADe), could revolutionize endoscopy. The adenoma detection rate (ADR) is inversely associated with the risk of postcolonoscopy colorectal cancer.1 The first CADe device approved in the United States (GI Genius; Medtronic, Minneapolis, MN) significantly increased the ADR and adenomas per colonoscopy (APC)2,3 and decreased the adenoma miss rate4 in randomized trials.