Progress in ovarian tissue cryopreservation in female fertility preservation

Ovary is an important reproductive organ of the female. It is a natural follicle pool which rich in many follicles at different developmental stages. Primitive follicles, which are concentrated in the ovarian cortex, are more tolerant to cryopreservation agent than growth follicles, so the cryopreservation of ovarian cortex tissue is a safer, effective and highly potential method for preserving female fertility. Ovarian tissue cryopreservation can preserve a large number of oocytes at one time. However, ovarian tissue cryopreservation is an experimental technology, and its clinical application is faced with many difficulties and obstacles. This article will focus on the technology and graft of ovarian tissue cryopreservation and its application and direction in female fertility preservation. Key words: Ovarian tissue; Cryopreservation; Fertility preservation