亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Cross-sectional study: Relationship between serum trace elements and hypertension

化学 微量元素 内科学 原子吸收光谱法 血压 内分泌学 胃肠病学 医学 量子力学 物理 有机化学
作者
Zhengduo Zhang,Shuyong Zhao,Zhenhua Wu,Wen Qin,Tianran Zhang,Yuxin Wang,Yanjin Tang,Shaojun Qi,Yiyao Cao,Xibao Gao
出处
期刊:Journal of Trace Elements in Medicine and Biology [Elsevier BV]
卷期号:69: 126893-126893 被引量:25
标识
DOI:10.1016/j.jtemb.2021.126893
摘要

A balanced intake of trace elements is beneficial for chronic diseases such as hypertension. However, the available information regarding trace elements that may be independently associated with hypertension is limited, and the relationship between this disorder and element ratios also remains unclear.A total of 6,754 subjects from rural China were selected, after exclusion of patients who were under 18, had incomplete data or had additional related disorders, by multi-stage simple random and cluster sampling (participation rate: 95.22 %). Subjects were divided into a hypertensive (H) and a control (C) group. Data were collected on blood pressure and 12 serum trace elements were measured by flame atomic absorption spectrometry and inductively coupled plasma-mass spectrometry. Other basic information was collated from questionnaires and biochemical indicators were measured via kits.Differences in serum levels of magnesium (Mg(mg/l): H: 27.43 ± 12.72; C: 26.33 ± 12.16), iron (Fe(mg/l): H: 1.99 ± 1.24; C: 1.84 ± 1.16), copper (Cu(mg/l): H: 1.19 ± 0.37; C: 1.10 ± 0.36), boron (B(μg/l): H: 50.00 ± 25.21; C: 47.57 ± 26.25), selenium (Se(μg/l): H: 125.12 ± 32.81; C: 118.80 ± 29.72) and chromium (Cr(μg/l): H: 8.77 ± 10.12; C: 10.12 ± 10.72) between the hypertensive and control groups were found. There were no differences in serum contents of calcium (Ca(mg/l): H: 112.43 ± 58.25; C: 111.00 ± 59.49), zinc (Zn(mg/l): H: 1.50 ± 1.97; C: 1.44 ± 1.88), arsenic (As(μg/l): H: 4.17 ± 3.94; C: 4.10 ± 4.00), manganese (Mn(μg/l): H: 4.15 ± 4.03; C: 4.07 ± 4.05), cadmium (Cd(μg/l): H: 1.14 ± 1.11; C: 1.18 ± 1.12) or lead (Pb(μg/l): H: 4.22 ± 8.90; C: 4.26 ± 10.25). The serum Cr and Cd concentrations of hypertensive men were lower than that of male controls while Mg, Cu, Ca and Se concentrations in male controls were lower. Further differences were apparent and Fe, B, Se, Mg and Cu all showed higher levels in hypertensive females whereas Cr concentrations were higher in female controls. Serum Zn and B levels showed age-related variations among hypertensive patients and concentrations of serum Cu, Zn, Se and B showed age-related variations among control subjects. For hypertensive patients, the odds ratio (OR) and 95 % confidence interval (CI) for the association of serum Cu, Se and Cr levels with hypertension were Cu: 1.36 (1.12-1.66); Se: 1.03 (1.01-1.05); Cr: 0.89 (0.83-0.96). Moreover, when the participants in the grouping with the highest copper/zinc (Cu/Zn) and magnesium/manganese (Mg/Mn) ratios were compared with the reference group, the OR and 95 % CI for hypertension were 1.22 (1.04-1.44) and 1.20 (1.01-1.42), respectively.Levels of serum trace elements showed age- and sex-related differences in a group of rural Chinese adults with hypertension and healthy participants. Serum concentrations of Cu, Se and Cr may be independently associated with hypertension. Higher serum ratios of Cu:Zn and Mg:Mn may also be associated with hypertension. Further randomized trials are necessary to elucidate the true relationship between levels of Cu, Se, Cr, Cu:Zn, Mg:Mn and hypertension.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
科研通AI5应助sljzhangbiao11采纳,获得10
2秒前
又来注水了完成签到,获得积分10
13秒前
快乐海豚完成签到 ,获得积分10
19秒前
科研通AI5应助科研通管家采纳,获得10
23秒前
科研狗的春天完成签到 ,获得积分10
26秒前
Lucas应助董可以采纳,获得10
33秒前
39秒前
Aqib发布了新的文献求助10
44秒前
45秒前
科研通AI5应助西瓜嘻嘻嘻采纳,获得10
48秒前
吴昕昕发布了新的文献求助10
50秒前
未晚完成签到 ,获得积分10
52秒前
香蕉觅云应助Aqib采纳,获得10
56秒前
早晨发布了新的文献求助10
1分钟前
孤鸿.完成签到 ,获得积分10
1分钟前
1分钟前
彭于晏应助11采纳,获得10
1分钟前
1分钟前
吴昕昕完成签到,获得积分10
1分钟前
1分钟前
iwaking完成签到,获得积分10
1分钟前
hxn发布了新的文献求助30
1分钟前
通通发布了新的文献求助10
1分钟前
早晨完成签到,获得积分10
1分钟前
Lucas应助通通采纳,获得10
1分钟前
1分钟前
WANG完成签到,获得积分10
1分钟前
有机发布了新的文献求助10
1分钟前
摆渡人完成签到,获得积分10
1分钟前
提桶跑路完成签到 ,获得积分10
1分钟前
温柔的天奇完成签到 ,获得积分10
1分钟前
实验耗材完成签到 ,获得积分10
1分钟前
1分钟前
lhlhl完成签到,获得积分10
1分钟前
1分钟前
1分钟前
小小林发布了新的文献求助10
2分钟前
zl13332完成签到 ,获得积分10
2分钟前
2分钟前
通通完成签到 ,获得积分10
2分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990020
求助须知:如何正确求助?哪些是违规求助? 3532077
关于积分的说明 11256276
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805139
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228