Synthesis of Three Dimensional Cs-γ-CD-MOFs and the Adsorption of Myricetin

A new Cs-γ-CD-MOF material obtained in colourless large crystals and with a three-dimensional porous structure containing coordinated by cesium ions and γ-cyclodextrin was synthesised by an improved vapour diffusion method. The chemical formula of the Cs-γ-CD-MOF material was C24H34CsO20, with the I4 space group. Compared with the traditional solvent vapour diffusion method (7 days), this method is advantageous for rapid crystal formation (1 day). Simultaneously, the drug adsortion capacity of γ-CD and Cs-γ-CD-MOFs for myricetin was compared and the results indicated that Cs-γ-CD-MOFs (280.05 mg g−1) have a higher drug adsorption capacity than γ-CD (142.92 mg g−1). Finally, the energy and conformation of the Cs-γ-CD-MOF material for adsorbing the drug myricetin were obtained through molecular docking.