药理学
促红细胞生成素受体
氧毒性
缺氧(环境)
化学
内科学
作者
Liasmine Haine,Céline-Hivda Yegen,Dominique Marchant,Jean-Paul Richalet,Emilie Boncoeur,Nicolas Voituron
标识
DOI:10.1016/j.biopha.2021.111547
摘要
Erythropoietin (Epo) is a pleiotropic cytokine, essential for erythropoiesis. Epo and its receptor (Epo-R) are produced by several tissues and it is now admitted that Epo displays other physiological functions than red blood cell synthesis. Indeed, Epo provides cytoprotective effects, which consist in prevention or fight against pathological processes. This perspective article reviews the various protective effects of Epo in several organs and tries to give a proof of concept about its effects in the lung. The tissue-protective effects of Epo could be a promising approach to limit the symptoms of acute and chronic lung diseases.
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