喹唑啉
组合化学
化学
小学(天文学)
结构-活动关系
生物活性
生物化学
体外
天文
物理
出处
期刊:Experimental Oncology
[LLC MORION]
日期:2019-04-05
卷期号:41 (1): 3-6
被引量:23
标识
DOI:10.32471/exp-oncology.2312-8852.vol-41-no-1.12414
摘要
Quinazolines are among the most useful heterocyclic compounds due to their diverse chemical reactivity and a wide range of biological activity. Despite a large number of publications devoted to quinazolines and their derivatives, information is presented predominantly regarding the features of the synthesis of these compounds and their structure. The studies of specific pharmacological activity and antitumor activity of these compounds are mainly limited to primary screening using enzyme systems and cell lines. In this mini review information concerning the potential targets for antitumor action of quinazoline compounds is summarized and discussed.
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