乙酰辅酶A羧化酶
脂肪生成
内科学
内分泌学
痤疮
丙酮酸羧化酶
化学
脂质代谢
酶
生物化学
医学
皮肤病科
作者
William P. Esler,Gregory J. Tesz,Marc K. Hellerstein,Carine Beysen,Raja K. Sivamani,Scott Turner,Steven M. Watkins,Paul A. Amor,Santos Carvajal‐Gonzalez,Frank J. Geoly,Kathleen Biddle,Julie J. Purkal,Mark Fitch,Clare Buckeridge,Annette M. Silvia,David A. Griffith,Matthew Gorgoglione,Lauren A. Hassoun,Suzana S. Bosanac,Nicholas B. Vera,Timothy P. Rolph,Jeffrey A. Pfefferkorn,Gabriele E. Sonnenberg
出处
期刊：Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期：2019-05-15
卷期号：11 (492)
被引量：48
标识
DOI：10.1126/scitranslmed.aau8465
摘要
De novo lipogenesis is essential for human sebum production, and increased lipogenic flux accounts for excessive sebum production in acne vulgaris.
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