An efficient method for producing tasty beer: characteristic bittering agents such as trans-isohumulone (1) can be obtained readily by photolysis of the hops extract in supercritical CO2 in an established industrial process without large losses incurred on boiling. Nontoxic, environmentally friendly, cheap, nonflammable, and applicable on a large scale—these assets of supercritical CO2 have long been recognized for extractions; this highlight shows that supercritical CO2 is also advantageous for many reactions.