纳米点
生物相容性
离子
光致发光
材料科学
分析化学(期刊)
检出限
激发态
核化学
量子点
选择性
纳米技术
化学
光电子学
催化作用
色谱法
核物理学
有机化学
冶金
物理
作者
Mani Vedamalai,Arun Prakash Periasamy,Chia‐Wei Wang,Yu‐Ting Tseng,Lin‐Chen Ho,Chung-Chien Shih,Huan‐Tsung Chang
出处
期刊:Nanoscale
[The Royal Society of Chemistry]
日期:2014-08-28
卷期号:6 (21): 13119-13125
被引量:230
摘要
A simple hydrothermal method was applied to prepare carbon nanodots (C dots) from o-phenylenediamine (OPD). The C dots exhibit photoluminescence at 567 nm when excited at 420 nm. In the presence of Cu(2+) ions, the colour of C dots changes from yellow to orange, with an increased PL intensity as a result of the formation of Cu(OPD)2 complexes on the surfaces of C dots. The D-band to G-band ratios of C dots in the absence and presence of 80 nM Cu(2+) ions are 1.31 and 4.75, respectively. The C dots allow the detection of Cu(2+) ions with linearity over a concentration range of 2-80 nM, with a limit of detection of 1.8 nM at a signal-to-noise ratio of 3. The cell viability values of A549, MCF-10A, and MDA-MB-231 cells treated with 3 μg mL(-1) of C dots are all greater than 99%, showing their great biocompatibility. Having great water dispersibility, photostability, chemical stability (against NaCl up to 0.5 M), great selectivity, and biocompatibility, the C dots have been employed for the localization of Cu(2+) ions in the cancer cells (A549 cells) treated with 10 μM Cu(2+) ions.
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