Transcutaneous electrical nerve stimulation as an adjunct for controlling chemotherapy-induced nausea and vomiting in gynecologic oncology patients

恶心 医学 止吐药 呕吐 交叉研究 安慰剂 经皮神经电刺激 化疗 麻醉 妇科肿瘤学 内科学 病理 替代医学
作者
Michael L. Pearl,Margaret Fischer,Dayna L. McCauley,Fidel A. Valea,Eva Chalas
出处
期刊:Cancer Nursing [Lippincott Williams & Wilkins]
卷期号:22 (4): 307-311 被引量:56
标识
DOI:10.1097/00002820-199908000-00008
摘要

Background: To evaluate the efficacy of a miniaturized portable transcutaneous electrical nerve stimulation (TENS) unit (ReliefBand) as an adjunct to standard antiemetic therapy for controlling nausea and vomiting induced by cisplatin-based chemotherapy in gynecologic oncology patients. Methods: Forty-two patients were enrolled in a randomized, double-blind, placebo-controlled parallel-subjects trial with a follow-up crossover trial. All patients received a standardized antiemetic protocol, then wore the ReliefBand continuously for 7 days. Results: Thirty-two patients were evaluable for the parallel-subjects component, 16 in each group. The percent-age of patients with absent or minimal nausea was 59% overall, which was similar to that for both the active (56%) and placebo (62%) groups. The incidence and severity of nausea and vomiting was similar for each group. Eighteen patients completed two consecutive cycles and were evaluable for the crossover component. The average age of the crossover patients and their dose intensity were comparable with those of the overall study population (56.3 versus 58.6 years and 22.7 versus 22.7 mg/m2/week, respectively). The percentage of cycles with absent or minimal nausea was 47% overall, which was similar to that of the active (50%) and placebo (44%) cycles. However, the severity of nausea was significantly lower in the active cycles during days 2 to 4. Patients averaged less than one episode of vomiting daily in each cycle. Conclusions: The ReliefBand is an effective adjunct to standard antiemetic agents for controlling nausea induced by cisplatin-based chemotherapy in gynecologic oncology patients.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
我是老大应助露亮采纳,获得10
2秒前
顾矜应助Bressanone采纳,获得10
2秒前
阳光发布了新的文献求助10
3秒前
半夏发布了新的文献求助10
4秒前
5秒前
6秒前
Miracle_wh完成签到,获得积分10
6秒前
7秒前
Miracle_wh发布了新的文献求助10
9秒前
11秒前
11秒前
12秒前
12秒前
圆月弯刀完成签到 ,获得积分10
13秒前
坦率白萱应助DJANGO采纳,获得30
15秒前
露亮完成签到,获得积分10
16秒前
Bressanone发布了新的文献求助10
16秒前
17秒前
斯文的慕儿完成签到 ,获得积分10
19秒前
露亮发布了新的文献求助10
19秒前
19秒前
智慧少女不头秃完成签到,获得积分10
21秒前
33完成签到,获得积分10
22秒前
所所应助感谢有你采纳,获得10
24秒前
24秒前
25秒前
26秒前
乐乐应助anna采纳,获得10
29秒前
潇湘雪月发布了新的文献求助10
29秒前
29秒前
刘燕发布了新的文献求助10
30秒前
30秒前
31秒前
量子星尘发布了新的文献求助10
34秒前
俏皮芷蕊发布了新的文献求助10
34秒前
35秒前
38秒前
38秒前
39秒前
Rondab应助张学友采纳,获得10
42秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989242
求助须知:如何正确求助?哪些是违规求助? 3531393
关于积分的说明 11253753
捐赠科研通 3270010
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882084
科研通“疑难数据库(出版商)”最低求助积分说明 809136