清脆的
生物
效应器
快照(计算机存储)
计算生物学
Cas9
基因组编辑
基因组工程
遗传学
流动遗传元素
基因组
计算机科学
基因
细胞生物学
操作系统
作者
Kira S. Makarova,Feng Zhang,Eugene V. Koonin
出处
期刊:Cell
[Elsevier]
日期:2017-01-01
卷期号:168 (1-2): 328-328.e1
被引量:165
标识
DOI:10.1016/j.cell.2016.12.038
摘要
Class 2 CRISPR-Cas systems are characterized by effector modules consisting of single, large, multidomain proteins that appear to have been derived from mobile genetic elements. Some Class 2 effector proteins, such as Cas9 and Cas12a (Cpf1), have been successfully repurposed for genome engineering.
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