基因组
管道(软件)
预处理器
计算机科学
软件
霰弹枪测序
数据挖掘
灵敏度(控制系统)
数据预处理
数据处理
作者
George Armstrong,Cameron Martino,Justin Morris,Behnam Khaleghi,Jaeyoung Kang,Jeff DeReus,Qiyun Zhu,Daniel Roush,Daniel McDonald,Antonio Gonazlez,Justin P. Shaffer,Carolina Carpenter,Mehrbod Estaki,Stephen Wandro,Sean Eilert,Ameen Akel,Justin Eno,Ken Curewitz,Austin D. Swafford,Niema Moshiri,Tajana Rosing,Rob Knight
出处
期刊:MSystems
[American Society for Microbiology]
日期:2022-03-16
标识
DOI:10.1128/msystems.01378-21
摘要
In shotgun metagenomics studies that seek to relate changes in microbial DNA across samples, processing the data on a computer often takes longer than obtaining the data from the sequencing instrument. Recently developed software packages that perform individual steps in the pipeline of data processing in principle offer speed advantages, but in practice they may contain pitfalls that prevent their use, for example, they may make approximations that introduce unacceptable errors in the data.
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