栀子花
环烯醚萜
葡萄糖苷
化学
玄参科
植物
传统医学
立体化学
糖苷
生物
医学
替代医学
病理
作者
Haibo Li,Yang Yu,Zhenzhong Wang,Yi Dai,Hao Gao,Wei Xiao,Xin‐Sheng Yao
出处
期刊:Fitoterapia
[Elsevier]
日期:2013-07-01
卷期号:88: 7-11
被引量:29
标识
DOI:10.1016/j.fitote.2013.03.025
摘要
Three new iridoid glucosides, 6″-O-trans-feruloylgenipin gentiobioside (1), 2′-O-trans-caffeoylgardoside (2), jasmigeniposide A (3), and one new bis-iridoid glucoside, jasmigeniposide B (4), along with six known analogues (5–10), were isolated from the fruit of Gardenia jasminoides. Their structures were established on the basis of spectroscopic analyses and chemical methods. Anti-virus activity of isolated compounds were evaluated in vitro and only compound 9 showed moderate inhibitory activity against H1N1 with 50% effective concentration (EC50) value of 104.36 μM, and selective index (SI) value greater than 4.79.
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