Comparative characterization of microstructure and luminescence of europium doped hydroxyapatite nanoparticles via coprecipitation and hydrothermal method

This paper reports the first attempt to compare the microstructure and luminescence of europium doped hydroxyapatite (HA) nanostructure to achieve strong and stable luminescence of hydroxyapatite nanophosphor, particularly, by co-precipitation and hydrothermal synthesis method. The Raman spectra analysis indicates that all modes are related to the HA phase. The morphology of Eu doped HA nanoparticles was depended on the synthesized method that was observed to have a nanowire structure to nanorod morphology. The creation of highly nanocrystalline Eu-doped HA with nanorod morphology resulted in a significantly enhancing luminescence of the nanophosphor, which was potential application in nanomedicine.