医学
痴呆
共病
抗胆碱能
初级保健医师
初级保健
老年病科
比尔斯标准
疾病
精神科
内科学
家庭医学
作者
Cathy C. Schubert,Malaz Boustani,Christopher M. Callahan,Anthony J. Perkins,Caroline P. Carney,Chris Fox,Frederick W. Unverzagt,Jason A. Dominitz,Hugh C. Hendrie
标识
DOI:10.1111/j.1532-5415.2005.00543.x
摘要
OBJECTIVES: To compare the medical comorbidity of older patients with and without dementia in primary care. DESIGN: Cross‐sectional study. SETTING: Wishard Health Services, which includes a university‐affiliated, urban public hospital and seven community‐based primary care practice centers in Indianapolis. PARTICIPANTS: Three thousand thirteen patients aged 65 and older attending seven primary care centers in Indianapolis, Indiana. MEASUREMENTS: An expert panel diagnosed dementia using International Classification of Diseases, 10th Revision , criteria. Comorbidity was assessed using 10 physician‐diagnosed chronic comorbid conditions and the Chronic Disease Score (CDS). RESULTS: Patients with dementia attending primary care have on average 2.4 chronic conditions and receive 5.1 medications. Approximately 50% of dementia patients in this setting are exposed to at least one anticholinergic medication, and 20% are prescribed at least one psychotropic medication. After adjusting for patients' age, race, and sex, patients with and without dementia have a similar level of comorbidity (mean number of chronic medical conditions, 2.4 vs 2.3, P =.66; average CDS, 5.8 vs 6.2, P =.83). CONCLUSION: Multiple medical comorbid conditions are common in older adults with and without dementia in primary care. Despite their cholinergic deficit, a substantial proportion of patients with dementia are exposed to anticholinergic medications. Models of care that incorporate this medical complexity are needed to improve the treatment of dementia in primary care.
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