Cognitive function and falling among older adults with mild cognitive impairment and slow gait

医学 认知 优势比 神经心理学 逻辑回归 老人忧郁量表 物理医学与康复 步态 萧条(经济学) 害怕跌倒 老年学 坠落(事故) 内科学 毒物控制 精神科 伤害预防 抑郁症状 经济 宏观经济学 环境卫生
作者
Takehiko Doi,Hiroyuki Shimada,Hyuntae Park,Hyuma Makizako,Kota Tsutsumimoto,Kazuki Uemura,Sho Nakakubo,Ryo Hotta,Takao Suzuki
出处
期刊:Geriatrics & Gerontology International [Wiley]
卷期号:15 (8): 1073-1078 被引量:69
标识
DOI:10.1111/ggi.12407
摘要

Aim To examine the association of the combination of slow gait and mild cognitive impairment ( MCI ) with cognitive function and falling in community‐dwelling older people. Methods Participants were selected from the O bu S tudy of H ealth P romotion for the E lderly ( n = 3400), and underwent gait examination and a battery of neuropsychological examinations, including the M ini‐ M ental S tate E xamination and the N ational C enter for G eriatrics and G erontology F unctional A ssessment T ool (tablet version of T rail M aking T est P art A and B , S ymbol D igit S ubstitution T ask, Figure selection task, W ord memory and S tory memory), and were interviewed with a series of questionnaires including medical history, physical activity, geriatric depression scale and fall history. Results Participants were classified into control ( n = 2281), slow gait speed ( SG ; n = 278), MCI ( n = 673) and MCI with SG ( MCI + SG ; n = 168) groups. All cognitive functions were significantly affected by the group factor, even adjusting for participant characteristics as covariates ( P < 0 .001). Post‐hoc analysis showed that the control group had better performance than the other groups, and the MCI + SG group had worse performance than the other groups in all cognitive functions (all P < 0.05). In multiple logistic regression analysis, SG and MCI were independently associated with falling (all P < 0.05), and MCI + SG had a higher odds ratio for falling (adjusted OR 1.99, 95% CI 1.08–3.65). Conclusions Our findings support the idea that slow gait and MCI were related, and concurrently associated with falling. Motor function among MCI subjects should be focused on to assess profile risks. Geriatr G erontol I nt 2015; 15: 1073–1078.
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