医学
置信区间
改良兰金量表
优势比
血管造影
冲程(发动机)
放射科
计算机断层血管造影
试验预测值
内科学
脑血管造影
心脏病学
缺血性中风
缺血
机械工程
工程类
作者
Audrey Nigron,Nathalie Bourgois,Salif Dao,C Lambert,Marie-Josée Perrier,Serge Akono,Ricardo Moreno,Emmanuel Chabert,Bourhis Jean,Béatrice Claise,Laurent Gerbaud,L. Boyer,Abderahim Zerroug
标识
DOI:10.1016/j.neurad.2019.03.016
摘要
To compare the evaluation of collaterals on multiphase computed tomography (CT) angiography using the score proposed by the reference study by Menon et al. and the Alberta Stroke Program Early CT (ASPECT) score for the prediction of favorable clinical outcome in patients with anterior ischemic stroke (IS). Retrospective single center study including 199 patients with anterior ischemic stroke and evaluated using multiphase CT angiography. Collaterals were assessed using the reference score and ASPECT score. The early clinical outcome [National Institute of Health Stroke Score (NIHSS) over day 1] and later clinical outcome [90-day modified Rankin Scale (mRS)] were collected. The primary analysis related to the association between collateral scores and clinical outcome. Collaterals are an independent predictive factor of favorable clinical outcome with the two scores, ranging from an odds ratio (OR) [95% confidence interval (CI)] = 1.84 [1.23; 2.76], P = 0.003 for the reference score to an OR [95% CI] = 2.63 [1.21; 5.73], p = 0.015 for the phase 3 ASPECT score. The phase 3 ASPECT score offers better sensitivity (Se) for the prediction of a favorable clinical outcome [Se = 95%, specificity (Sp) = 37% for a threshold of 7/7] than the reference score (Se = 83%, Sp = 47% for a threshold of 4/5). This study demonstrates the value of the ASPECT score in analyzing collaterals using multiphase CT angiography for the prediction of clinical outcome.
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