Gefitinib with or without pemetrexed in nonsquamous (NS) non-small cell lung cancer (NSCLC) with EGFR mutation (mut): Final overall survival (OS) results from a randomized phase II study

Background: The combination of pemetrexed (P)-based chemotherapy with EGFR-tyrosine kinase inhibitors (TKI) has resulted in improved efficacy vs EGFR-TKI alone for treatment (tx) of advanced NSCLC with EGFR-mut. The objective of this disclosure is to report OS, updated progression-free survival (PFS), and safety of P+Gefitinib (G) vs G alone in patients (pts) with advanced NS NSCLC with EGFR-mut.