化学
试剂
铟
氯化物
水介质
有机化学
水溶液
组合化学
作者
J. S. Yadav,B. V. Subba Reddy,Ch. Reddy,A. Krishna
出处
期刊:Synthesis
[Georg Thieme Verlag KG]
日期:2007-02-22
卷期号:2007 (5): 693-696
被引量:33
标识
DOI:10.1055/s-2007-965930
摘要
Indoles and azaindoles undergo smooth oxidation with 2-iodoxybenzoic acid (IBX) in the presence of indium(III) chloride at 80 °C to afford the corresponding isatins in excellent yields. This method is very useful for the direct preparation of isatins from indoles. The reaction proceeds smoothly in aqueous media and the products are obtained in excellent yields.
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