Impact of Initial Filling Medium on Outcomes of Subpectoral Two-Stage Implant-Based Breast Reconstruction: Air Versus Saline

In two-stage expander-based breast reconstruction, the use of air as the initial filling medium has been suggested to confer clinical advantages over conventional saline, but this has not been demonstrated in a large series. This study aimed to evaluate the association between material type (air versus saline) for initial expander filling and postoperative outcomes.