Contact ratio and adaptations in the maxillary and mandibular dentoalveolar joints in rats and human clinical analogs

牙周纤维 臼齿 牙骨质 医学 牙科 下颌骨(节肢动物口器) X射线显微断层摄影术 口腔正畸科 下颌第二磨牙 材料科学 解剖 生物 牙本质 植物 放射科
作者
B. Wang,Nam P. Nguyen,Misun Kang,Sudarshan Srirangapatanam,Stephen Connelly,Richard Demo Souza,Sunita P. Ho
出处
期刊:Journal of The Mechanical Behavior of Biomedical Materials [Elsevier BV]
卷期号:136: 105485-105485 被引量:1
标识
DOI:10.1016/j.jmbbm.2022.105485
摘要

Spatial maps of function-based contact areas and resulting mechanical strains in bones of intact fibrous joints in preclinical small-scale animal models are limited. Functional imaging in situ on intact dentoalveolar fibrous joints (DAJs) in hemimandibles and hemimaxillae harvested from 10 male Sprague-Dawley rats (N = 5 at 12 weeks, N = 5 at 20 weeks) was performed in this study. Physical features including bone volume fraction (BVF), bone pore diameter and pore density, and cementum fraction (CF) of the molars in the maxillary and mandibular joints were evaluated. Biomechanical testing in situ provided estimates of joint stiffness, changes in periodontal ligament spaces (PDL-space) between the molar and bony socket, and thereby localization of contact area in the respective joints. Contact area localization revealed mechanically stressed interradicular and apical regions in the joints. These anatomy-specific contact stresses in maxillary and mandibular joints were correlated with the physical features and resulting strains in interradicular and bony socket compartments. The mandibular joint spaces, in general, were higher than maxillary, and this trend was consistent with age (younger loaded: Mn - 134 ± 55 μm, Mx - 110 ± 47 μm; older loaded: Mn - 122 ± 49 μm, Mx - 105 ± 48 μm). However, a significant decrease (P < 0.05) in mandibular and maxillary joint spaces with age (younger unloaded: Mn - 147 ± 51 μm; Mx - 125 ± 42 μm; older unloaded: Mn - 134 ± 46 μm; Mx - 116 ± 44 μm) was observed. The bone volume fraction (BVF) of mandibular interradicular bone (IR bone) increased significantly with age (P < 0.05) with the percent porosity of coronal mandibular bone lower than its maxillary counterpart. The contact ratio (contact area to total surface area) of maxillary teeth was significantly greater (P < 0.05) than mandibular teeth; both maxillary interradicular and apical contact ratios (IR bone: 41%, 56%; Apical bone: 4%, 12%) increased with age, and were higher than the mandibular (IR bone: 19%, 44%; Apical bone: 1%, 4%) counterpart. Resulting higher but uniform strains in maxillary bone contrasted with lower but higher variance in mandibular strains at a younger age. Anatomy-specific colocalization of physical properties and functional strains in bone provided insights into form-guided adaptive dominance of the maxilla compared to material property-guided adaptive dominance of the mandible. These age-related trends from the preclinical animal model paralleled with age- and tooth position-specific variabilities in mandibular craniofacial bones of adolescent and adult patients following orthodontic treatment.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
罗拉发布了新的文献求助10
刚刚
1秒前
1秒前
鱼e完成签到,获得积分10
3秒前
3秒前
4秒前
4秒前
song发布了新的文献求助10
6秒前
ding应助时尚初之采纳,获得10
6秒前
罗拉完成签到,获得积分10
6秒前
6秒前
7秒前
yun尘世完成签到,获得积分10
8秒前
8秒前
自信南霜完成签到,获得积分10
8秒前
tingting9完成签到,获得积分10
11秒前
11秒前
12秒前
卡布奇诺完成签到,获得积分10
12秒前
13223456发布了新的文献求助10
12秒前
青山落日秋月春风完成签到,获得积分10
14秒前
15秒前
16秒前
16秒前
小马甲应助动听的雅绿采纳,获得30
17秒前
1177发布了新的文献求助10
19秒前
19秒前
喜喵喵完成签到,获得积分10
20秒前
20秒前
20秒前
20秒前
11关注了科研通微信公众号
21秒前
123456完成签到,获得积分10
22秒前
时尚初之发布了新的文献求助10
22秒前
ddd完成签到,获得积分10
23秒前
喜喵喵发布了新的文献求助10
25秒前
无情的函发布了新的文献求助10
25秒前
麦乐迪完成签到 ,获得积分10
26秒前
SYLH应助云横秦岭家何在采纳,获得10
26秒前
bkagyin应助如意枫叶采纳,获得10
27秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989242
求助须知:如何正确求助?哪些是违规求助? 3531393
关于积分的说明 11253753
捐赠科研通 3270010
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882084
科研通“疑难数据库(出版商)”最低求助积分说明 809136