Vitality, mental health and role-physical mediate the influence of coping on depressive symptoms and self-efficacy in patients with non-alcoholic fatty liver disease: A cross-sectional study

活力 脂肪肝 应对(心理学) 糖尿病 医学 体质指数 内科学 心理健康 肥胖 临床心理学 横断面研究 心理学 疾病 精神科 内分泌学 病理 哲学 神学
作者
Jesús Funuyet‐Salas,María Ángeles Pérez-San-Gregorio,Agustín Martín Rodríguez,Manuel Romero‐Gómez
出处
期刊:Journal of Psychosomatic Research [Elsevier]
卷期号:162: 111045-111045 被引量:4
标识
DOI:10.1016/j.jpsychores.2022.111045
摘要

Objective: Our aim was to determine whether the association between active coping and depressive symptoms in patients with non-alcoholic fatty liver disease (NAFLD) was mediated by vitality, and whether diabetes and obesity could impact on this relationship.We also wanted to find out whether mental health and role-physical modulated the relationship between passive/avoidance coping and self-efficacy, and the role of liver fibrosis.Methods: Depressive symptoms (BDI-II), self-efficacy (GSE), coping (COPE-28) and quality of life (SF-12) were evaluated in 509 biopsy-proven NAFLD patients in this cross-sectional study.Mediation and moderated mediation models were conducted using the SPSS PROCESS v3.5 macro.Results: Vitality mediated the relationship between active coping and depressive symptoms (-2.254,CI = -2.792 to -1.765), with diabetes (-0.043, p = 0.017) and body mass index (BMI) (-0.005, p = 0.009) moderating the association.In addition, mental health (-6.435,CI = -8.399 to -4.542) and role-physical (-1.137,CI = -2.141 to -0.315) mediated the relationship between passive/avoidance coping and self-efficacy, with fibrosis stage (0.367, p < 0.001) moderating this association.Specifically, the presence of diabetes and significant fibrosis, and a higher BMI, were associated with greater negative impact on participant depressive symptoms or self-efficacy.Conclusion: A maladaptive coping style was associated with poorer vitality, mental health and role-physical in NAFLD patients, which along with the presence of metabolic comorbidity (diabetes and obesity) and significant fibrosis predicted more depressive symptoms or poorer self-efficacy in these patients.These results suggested incorporating emotional and cognitive evaluation and treatment in patients with NAFLD.
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