已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

380. UTILITY OF PET/CT FOR LYMPH NODE METASTASIS DETECTION IN PT1 EARLY ESOPHAGEAL SQUAMOUS CELL CARCINOMA

医学 食管鳞状细胞癌 正电子发射断层摄影术 淋巴结 放射科 PET-CT 队列 转移 回顾性队列研究 内科学 核医学 肿瘤科 癌症
作者
Jiaqi Xu,Siyun Lin,Quan‐Lin Li,Ping‐Hong Zhou,Lijie Tan
出处
期刊:Diseases of The Esophagus [Oxford University Press]
卷期号:35 (Supplement_2)
标识
DOI:10.1093/dote/doac051.380
摘要

Abstract Nodal staging for early esophageal squamous cell carcinoma (ESCC) was mandatory to decide therapy strategy. Utility of preoperative Positron Emission Tomography/Computed Tomography (PET/CT) for lymph node metastasis (LNM) detection in early ESCC was evaluated in the study. 186 consecutive patients with pathologically confirmed T1 tumors undergoing preoperative PET/CT at Zhongshan Hospital between 2015 August to 2020 December were retrospectively enrolled. Clinical characteristics and PET/CT results were collected and compared between patients with or without LNM. A PET integrated risk score model for prediction of LNM was established and validated. Survivals were compared between high risk group and low risk group by Log Rank test. 40 out of 186 patients were diagnosed with LNM on PET-CT. PET/CT alone for LNM detection was with a 53.3% sensitivity, 84.65% specificity, and 90.4% negative predictive value. Tumor size >2.5 cm (P = 0.015), tumor depth (P = 0.012), LVI (P < 0.001), differentiation (P = 0.066) and PET LN (+) (P < 0.001) were included in the prediction model for LNM. The AUC of ROC in derivation cohort and validation cohort was 0.860 and 0.846 respectively. High risk group scoring >3 points showed poorer 5-year recurrence free survival (62.6% VS. 74.7%, P = 0.046) and similar overall survival (87.6% VS. 86.9%, P = 0.942) as compared to low risk group. PET/CT for LNM detection in early ESCC was of 53.3% sensitivity and 84.65% specificity. PET integrated risk score model for LNM was of fair property with 0.860 AUC and was predictive of recurrence.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
大个应助科研通管家采纳,获得10
刚刚
刚刚
bxxxxx应助科研通管家采纳,获得10
刚刚
Orange应助科研通管家采纳,获得10
1秒前
汉堡包应助科研通管家采纳,获得10
1秒前
超帅冬易完成签到,获得积分10
1秒前
1秒前
wkjfh应助一方通行采纳,获得10
1秒前
2秒前
momo发布了新的文献求助10
3秒前
3秒前
至秦完成签到,获得积分10
4秒前
5秒前
5秒前
7秒前
头头啊头头啊完成签到,获得积分10
7秒前
Notdodead应助畅通无阻采纳,获得10
7秒前
至秦发布了新的文献求助30
7秒前
张兔子发布了新的文献求助10
9秒前
科研通AI2S应助132采纳,获得30
10秒前
wimper发布了新的文献求助10
13秒前
wimper完成签到,获得积分10
18秒前
18秒前
20秒前
小药同学发布了新的文献求助10
21秒前
22秒前
Pu Chunyi发布了新的文献求助10
25秒前
漂亮白枫发布了新的文献求助10
25秒前
程程发布了新的文献求助10
27秒前
30秒前
30秒前
刺闰土的猹完成签到,获得积分10
30秒前
星辰大海应助漂亮白枫采纳,获得10
31秒前
学术圈边缘派遣员完成签到,获得积分10
31秒前
32秒前
33秒前
小肉包发布了新的文献求助10
36秒前
36秒前
36秒前
38秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989811
求助须知:如何正确求助?哪些是违规求助? 3531927
关于积分的说明 11255560
捐赠科研通 3270706
什么是DOI,文献DOI怎么找? 1805035
邀请新用户注册赠送积分活动 882181
科研通“疑难数据库(出版商)”最低求助积分说明 809190