紫苏
敏化
紫苏
过敏
医学
皮肤病科
传统医学
免疫学
化学
原材料
有机化学
作者
Jun Shirota,Hiroko Sakuma,Fumi Mashiyama,Naoko Suzuki,Yuka Takeda,Hisao Okabe,Hikaru Sugita,Yasuto Kondo
出处
期刊:PubMed
日期:2024-01-01
卷期号:73 (3): 290-293
标识
DOI:10.15036/arerugi.73.290
摘要
Herein, we report the case of a 7-year-old girl with a history of atopic dermatitis because of infancy. Her grandfather grew Egoma (Perilla frutescens), and her family frequently consumed food items prepared using Egoma; however, she never consumed them because she did not enjoy these food items; she experienced vomiting, facial swelling, and oral discomfort upon ingesting Egoma during school lunch for the first time. Her food oral challenge test was positive, as well as a skin-prick test with sesame powder. Egoma antigen protein was extracted and reacted with patient serum by immunoblotting, which detected a positive band of approximately 26kDa. She was brought up in an environment with high exposure to Egoma; hence, she most likely developed an allergy to Egoma because of percutaneous sensitization. This is the first time an Egoma allergen analysis has been conducted in Japan, and we consider it to be a valuable case.
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