神经母细胞瘤
增强子
背景(考古学)
生物
癌症研究
基因
发病机制
癌症
基因表达
细胞生物学
遗传学
免疫学
细胞培养
古生物学
作者
Jianwei Wang,Ran Zhuo,Liguang Sun,Tao Yan,Gen Li,Frank Zhu,Yun Yun Xu,Jianwei Wang,Zhi Heng Li,Juan Juan Yu,Hong Yin,Di Wu,Xiaolu Li,Fang Fang,Yi Xie,Yingwei Hu,Hairong Wang,Chun Yang,Lei Shi,Xiaodong Wang,Z. Zhang,Jian Pan
出处
期刊:Neuro-oncology
[Oxford University Press]
日期:2024-06-12
标识
DOI:10.1093/neuonc/noae109
摘要
Super-enhancers (SEs) typically govern the expression of critical oncogenes and play a fundamental role in the initiation and progression of cancer. Focusing on genes that are abnormally regulated by SE in cancer may be a new strategy for understanding pathogenesis. In the context of this investigation, we have identified a previously unreported SE-driven gene IRF2BP2 in neuroblastoma (NB).
科研通智能强力驱动
Strongly Powered by AbleSci AI