生物
多倍体
基因组
进化生物学
遗传学
生物技术
计算生物学
基因
作者
Yazhong Wang,Roven Rommel Fuentes,Willem M. J. van Rengs,Sieglinde Effgen,Mohd Waznul Adly Mohd Zaidan,Rainer Franzen,Tamara Susanto,Joiselle Blanche Fernandes,Raphaël Mercier,Charles J. Underwood
标识
DOI:10.1038/s41588-024-01750-6
摘要
Abstract Heterosis boosts crop yield; however, harnessing additional progressive heterosis in polyploids is challenging for breeders. We bioengineered a ‘mitosis instead of meiosis’ ( MiMe ) system that generates unreduced, clonal gametes in three hybrid tomato genotypes and used it to establish polyploid genome design. Through the hybridization of MiMe hybrids, we generated ‘4-haplotype’ plants that encompassed the complete genetics of their four inbred grandparents, providing a blueprint for exploiting polyploidy in crops.
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