化学
烷基
卤素
联轴节（管道）
卤键
药物化学
立体化学
有机化学
组合化学
机械工程
工程类
作者
Guoliang Pu,Shi-Yuan Song,Yang Jian,Peng Guo,Jia Jia,Peijun Liu,Xuefei Li,Ping Liu,Chun‐Yang He
摘要
A practical method for the cross-coupling of ethyl 3-bromo-3-alkyl-2,2-difluoropropanoates with coumarins/quinolinones was developed. The IC 50 values of 3l against Huh-7 and A549 cells were determined to be 4.6 μM and 6.8 μM, respectively.
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