Glycal mediated synthesis of piperidine alkaloids: fagomine, 4-epi-fagomine, 2-deoxynojirimycin, and an advanced intermediate, iminoglycal

Synthesis of fagomine, 4- epi -fagomine, formal synthesis of nojirimycin, nojirimycin B, & 2-deoxynojirimycin has been carried out using Super-Hydride reduction as a key step. DFT studies explain the failure of the reduction of galactolactam substrate.