化学
环加成
钯
催化作用
配体(生物化学)
组合化学
药物化学
立体化学
有机化学
受体
生物化学
作者
Zhen‐Hua Wang,Xiaohui Fu,Qun Li,Jian‐Qiang Zhao,Yong You,Yanping Zhang,Wei‐Cheng Yuan
出处
期刊:Organic Letters
[American Chemical Society]
日期:2024-02-22
卷期号:26 (8): 1589-1594
被引量:5
标识
DOI:10.1021/acs.orglett.3c04339
摘要
This study demonstrates a highly efficient regiodivergent ligand-controlled palladium-catalyzed cycloaddition reaction of vinyloxazolidine-2,4-diones with 1,3,5-triazinanes. In the presence of a diphosphine ligand, the reaction proceeds via a (5+2) cycloaddition pathway to afford 1,3-diazepin-4-ones in excellent yields, while using a monophosphine ligand, the reaction proceeds smoothly via a (3+2) cycloaddition pathway to give imidazolidin-4-ones in good yields.
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