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LettersFebruary 2024Acupuncture and Doxylamine–Pyridoxine for Nausea and Vomiting in PregnancyQi Wang, MDQi Wang, MDChina Academy of Engineering, National Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing, ChinaAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L23-0426 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR: Wu and colleagues (1) investigated the efficacy and safety of acupuncture, doxylamine–pyridoxine, or both for moderate to severe NVP. Clinical practice guidelines currently do not recommend acupuncture for NVP because of unclear benefits (2), but Wu and colleagues' trial supports its use for NVP with high-quality evidence. This new and larger trial shows the efficacy of acupuncture by adopting a daily acupuncture protocol treating moderate to severe NVP with additional stimulation on acupoints PC6 and ST36 (known as Neiguan and Zusanli) as core acupoints and 1 adjuvant acupoint selected on the basis of traditional Chinese medicine (TCM) ...References1. Wu XK, Gao JS, Ma HL, et al. Acupuncture and doxylamine–pyridoxine for nausea and vomiting in pregnancy. A randomized, controlled, 2 × 2 factorial trial. Ann Intern Med. 2023;176:922-933. [PMID: 37335994] doi:10.7326/M22-2974 LinkGoogle Scholar2. Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin no. 189: nausea and vomiting of pregnancy. Obstet Gynecol. 2018;131:e15-e30. [PMID: 29266076] doi:10.1097/AOG.0000000000002456 CrossrefMedlineGoogle Scholar3. Jiang M, Lu C, Zhang C, et al. Syndrome differentiation in modern research of traditional Chinese medicine. J Ethnopharmacol. 2012;140:634-42. [PMID: 22322251] doi:10.1016/j.jep.2012.01.033 CrossrefMedlineGoogle Scholar4. Fei YT, Cao HJ, Xia RY, et al. Methodological challenges in design and conduct of randomised controlled trials in acupuncture. BMJ. 2022;376:e064345. [PMID: 35217507] doi:10.1136/bmj-2021-064345 CrossrefMedlineGoogle Scholar5. Wang Q. Applying TCM constitution theory to infertility via omics. Engineering. 19 May 2023. doi:10.1016/j.eng.2023.05.005 CrossrefGoogle Scholar Author, Article, and Disclosure InformationAuthors: Qi Wang, MDAffiliations: China Academy of Engineering, National Institute of TCM Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing, ChinaDisclosures: Authors have reported no disclosures of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L23-0426. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAcupuncture and Doxylamine–Pyridoxine for Nausea and Vomiting in Pregnancy Xiao-Ke Wu , Jing-Shu Gao , Hong-Li Ma , Yu Wang , Bei Zhang , Zhao-Lan Liu , Jian Li , Jing Cong , Hui-Chao Qin , Xin-Ming Yang , Qi Wu , Xiao-Yong Chen , Zong-Lin Lu , Ya-Hong Feng , Xue Qi , Yan-Xiang Wang , Lan Yu , Ying-Mei Cui , Chun-Mei An , Li-Li Zhou , Yu-Hong Hu , Lu Li , Yi-Juan Cao , Ying Yan , Li Liu , Yu-Xiu Liu , Zhi-Shun Liu , Rebecca C. Painter , Ernest H.Y. Ng , Jian-Ping Liu , Ben Willem J. Mol , and Chi Chiu Wang Acupuncture and Doxylamine–Pyridoxine for Nausea and Vomiting in Pregnancy Jing-Shu Gao , Hong-Li Ma , Chi Chiu Wang , Tian Xie , Xiao-Ke Wu Acupuncture and Doxylamine–Pyridoxine for Nausea and Vomiting in Pregnancy Arthur Yin Fan , and Sherman Gu Metrics Current IssueFebruary 2024Volume 177, Issue 2KeywordsAcupunctureNauseaPregnancyRandomized trialsVomiting ePublished: 20 February 2024 Issue Published: February 2024 Copyright & PermissionsCopyright © 2024 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...