Nitrous oxide provided during intensive physiotherapy for shoulder adhesive capsulitis does not improve function: A randomised controlled trial

医学 物理疗法 安慰剂 荚膜炎 康复 随机对照试验 运动范围 临床试验 不利影响 外科 内科学 病理 替代医学
作者
Arnaud Dupeyron,Lech Dobija,Christel Castelli,S Petiot,Isabelle Tavares,Anthony Gélis,Emmanuel Coudeyre
出处
期刊:Annals of Physical and Rehabilitation Medicine 卷期号:67 (3): 101803-101803
标识
DOI:10.1016/j.rehab.2023.101803
摘要

There is no consensus on treatment for adhesive capsulitis of the shoulder. Physiotherapy is often used to increase range of motion but individuals may experience pain during mobilisation. The objective of this study was to determine whether rehabilitation under N2O for shoulder AC improved pain and function more than rehabilitation alone (with placebo gas). A randomised, 1:1 parallel arm, double-blind study in 4 university hospital outpatient centres. Adults with adhesive capsulitis for at least 3 months with intact cartilage were included. Participants were randomised in blocks of 4 and stratified by centre to receive 20 sessions of intensive physiotherapy over 10 days; the 10 morning sessions were performed with either nitrous oxide (intervention) or sham gas (placebo). Primary outcome: improvement in shoulder function at day 14 (D14) (Constant-Murley score). Seventy-five participants were included, and data from 69 were analysed: 37 in the placebo group and 32 in the intervention group. Improvements occurred in both groups after the intervention. No significant difference in the Constant-Murley score was found between groups at D14 (median score increase of 12.0, IQR 5.6; 19.5 points in placebo group vs. 13.7, 5.2; 18.2 in the N20 group, p = 0.78). Pain score during sessions reduced in the intervention group from the first to final session (−11.6, p = 0.053) but not for the placebo group (−4.2, p = 0.414). Seven serious adverse events were recorded, 4 in the intervention group and 3 in the placebo group, with 11 minor adverse events only in the intervention group (mostly shortness of breath). Nitrous oxide gas associated with intensive physiotherapy for shoulder adhesive capsulitis did not improve function, pain or quality of life more than physiotherapy alone. zHowever, pain experienced during physiotherapy sessions appeared lower. Clinical Trial registration number NCT01087229.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
zz完成签到,获得积分10
刚刚
Popeye应助阿胡采纳,获得30
1秒前
2秒前
魁魁完成签到,获得积分20
2秒前
PEKIEOKE发布了新的文献求助30
3秒前
3秒前
无语的凡梦完成签到,获得积分10
4秒前
wanci应助二十四桥明月夜采纳,获得10
5秒前
风清扬应助LaTeXer采纳,获得10
5秒前
leo关闭了leo文献求助
6秒前
推土机爱学习完成签到 ,获得积分10
6秒前
李萍萍发布了新的文献求助10
6秒前
6秒前
fdwang完成签到 ,获得积分10
6秒前
清漪完成签到 ,获得积分10
7秒前
深情安青应助海白采纳,获得10
7秒前
晴栀完成签到,获得积分10
7秒前
hetao286完成签到,获得积分10
8秒前
阿三的风光完成签到 ,获得积分10
8秒前
nature完成签到 ,获得积分10
8秒前
量子星尘发布了新的文献求助10
9秒前
科研狗完成签到 ,获得积分10
10秒前
追光者完成签到,获得积分10
10秒前
HJJHJH发布了新的文献求助10
11秒前
Advance.Cheng发布了新的文献求助10
11秒前
传统的大白完成签到,获得积分10
11秒前
复杂的白秋完成签到,获得积分10
12秒前
12秒前
舒适的平蓝完成签到,获得积分10
13秒前
DAI123完成签到,获得积分10
13秒前
13秒前
阳yang发布了新的文献求助10
13秒前
HIH完成签到 ,获得积分10
14秒前
可靠的寒风完成签到,获得积分10
15秒前
Pan完成签到,获得积分10
15秒前
16秒前
16秒前
16秒前
丢丢丢完成签到,获得积分10
16秒前
安静的ky完成签到,获得积分10
16秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038426
求助须知:如何正确求助?哪些是违规求助? 3576119
关于积分的说明 11374556
捐赠科研通 3305834
什么是DOI,文献DOI怎么找? 1819339
邀请新用户注册赠送积分活动 892678
科研通“疑难数据库(出版商)”最低求助积分说明 815029