医学
哮喘
怀孕
后代
优势比
队列
呼吸音
特应性皮炎
队列研究
儿科
过敏
过敏性
体质指数
内科学
免疫学
遗传学
生物
作者
Elina Sivula,Heidi Puharinen,Sari Hantunen,Leea Keski‐Nisula,Katri Backman
摘要
Abstract Background Several recent studies have investigated the association between maternal diet during pregnancy and wheezing or asthma in children. However, whether a specific dietary pattern during pregnancy protects children from wheezing or atopic diseases remains unclear. This study investigated the association between The Alternative Healthy Eating Index for Pregnancy (AHEI‐P), the Dietary Inflammatory Index (DII), and the risk for wheezing and atopic eczema in children during the first year of life. Methods This study included 1330 mother–child pairs who attended the Kuopio Birth Cohort (KuBiCo) study and had dietary information during the last trimester and information on children's health in the first year of life. AHEI‐P and DII indicate a healthy diet and dietary inflammation potential during pregnancy. The AHEI‐P and DII were compared with reported wheezing and doctor‐diagnosed atopic eczema in children during the first year of life. Results Neither AHEI‐P nor DII is associated with wheezing or atopic eczema in children when analyzed by continuous variables and by tertiles. The odds ratio (95% CI) for AHEI‐P and wheezing was 0.99 (0.98–1.01), for AHEI‐P and atopic eczema1.01 (0.99–1.02), for DII and wheezing 1.02 (0.95–1.09), and for DII and atopic eczema 0.97 (0.91–1.04). Conclusion In this cohort study, AHEI‐P and DII during pregnancy were not associated with wheezing or atopic eczema in the offspring during the first year of life.
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