药效学
药代动力学
炎症体
药理学
医学
内科学
受体
作者
Giulia D’Urso,Alessandra E. Thomann,Judith Anzures‐Cabrera,Bastian Zinnhardt,Benedicte Ricci,Lorna E. Bailey,Krzysztof Śmigórski,Venissa Machado,Eva Zsuszsanna Mracskó,Nicola Pavese,Kenneth Marek,Kathrin Brockmann,Tanya Simuni,Nicoletta Milani Muelhardt,Gennaro Pagano
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2023-04-25
卷期号:100 (17_supplement_2)
标识
DOI:10.1212/wnl.0000000000203618
摘要
Here we describe the study design of a Phase Ib study to test the safety, pharmacokinetics and pharmacodynamics of selnoflast, a novel NLRP3 inflammasome inhibitor, in individuals with early-stage PD.
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