化学
胺气处理
碳氢化合物
适应性
螺旋(腹足类)
有机化学
组合化学
化学工程
生态学
生物
工程类
蜗牛
作者
Daniel C. Tran,Thanh K. Pham,Young‐Woo Kim
标识
DOI:10.1016/j.bmc.2024.117893
摘要
This study comprehensively explored the helix-stabilizing effects of amine-bearing hydrocarbon cross-links (ABXs), revealing their context-dependent nature influenced by various structural parameters. Notably, we identified a 9-atom ABX as a robust helix stabilizer, showcasing versatile synthetic adaptability while preserving peptide water solubility. Future investigations are imperative to fully exploit this system's potential and enrich our chemical toolkit for designing innovative peptide-based biomolecules.
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