纳米载体
热重分析
材料科学
傅里叶变换红外光谱
药物输送
透射电子显微镜
碳纳米管
纳米材料
纳米-
纳米颗粒
核化学
化学工程
纳米技术
扫描电子显微镜
化学
复合材料
有机化学
工程类
作者
Burcu Aydoğdu,Olcay Kaplan İnce,Muharrem İnce,İlkay Ünal
标识
DOI:10.1002/slct.202402051
摘要
Abstract Multi‐walled carbon nanotubes (fMWCNTs) that functionalized and loaded Ag nanoparticles (AgNPs) were investigated to adsorp doxorubicin hydrochloride (DXR). DXR release behavior efficiency was determined using kinetic studies. DXR agent was treated into fMWCNTs@AgNPs material with different drug loading rates. The material was successfully established and characterized using transmission electron microscopy, and fourier transform–infrared spectroscopy. Thermogravimetric analysis was performed to elucidate the effect of temperature on mass loss and X‐ray diffraction analysis was systematically assessed the crystalline state of DXR. Various kinetic models including Higuchi, Baker Hixson‐Crowell, and power‐law were applied. It was revealed that DXR has more binding affinity to the fMWCNTs@AgNPs material system surface as a nanocarrier at pH 7.4 and showed more release at pH 5.0. Functionalized material confirmed its efficiency as pH‐based drug delivery system. Used material can be utilized as promising nanocarriers, and findings will contribute to the rational design of novel delivery tools for drugs.
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