医学
慢性阻塞性肺病
表型
肺病
重症监护医学
内科学
计算生物学
遗传学
基因
生物
作者
Alexander J. Bell,Sundaresh Ram,Wassim W. Labaki,Susan Murray,Ella A. Kazerooni,Stefanie Galbán,Fernando J. Martinez,Charles R. Hatt,Jennifer M Wang,Vladimir Ivanov,Paul McGettigan,Edward Khokhlovich,Enrico Maiorino,Rahul Suryadevara,Adel Boueiz,Peter J. Castaldi,Evgeny M. Mirkes,Andreï Zinovyev,Alexander N. Gorban,Craig J. Galbán,MeiLan K. Han
标识
DOI：10.1164/rccm.202401-0127oc
摘要
Chronic obstructive pulmonary disease (COPD) exhibits considerable progression heterogeneity. We hypothesized that elastic principal graph analysis (EPGA) would identify distinct clinical phenotypes and their longitudinal relationships.
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