Coffee and alcohol consumption and the risk of pancreatic cancer in two prospective United States cohorts.

医学 前瞻性队列研究 胰腺癌 置信区间 队列 队列研究 相对风险 环境卫生 咖啡因 癌症 人口学 内科学 社会学
作者
Dominique S. Michaud,Edward L. Giovannucci,Walter C. Willett,Graham A. Colditz,C S Fuchs
出处
期刊:PubMed 卷期号:10 (5): 429-37 被引量:131
链接
标识
摘要

Although most prospective cohort studies do not support an association between coffee consumption and pancreatic cancer, the findings for alcohol are inconsistent. Recently, a large prospective cohort study of women reported statistically significant elevations in risk of pancreatic cancer for both coffee and alcoholic beverage consumption. We obtained data on coffee, alcohol, and other dietary factors using semiquantitative food frequency questionnaires administered at baseline (1986 in the Health Professionals Follow-Up Study and 1980 in the Nurses' Health Study) and in subsequent follow-up questionnaires. Data on other risk factors for pancreatic cancer, including cigarette smoking, were also available. Individuals with a history of cancer at study initiation were excluded from all of the analyses. During the 1,907,222 person-years of follow-up, 288 incident cases of pancreatic cancer were diagnosed. The data were analyzed separately for each cohort, and results were pooled to compute overall relative risks (RR). Neither coffee nor alcohol intakes were associated with an increased risk of pancreatic cancer in either cohort or after pooling the results (pooled RR, 0.62; 95% confidence interval, 0.27-1.43, for >3 cups of coffee/day versus none; and pooled RR, 1.00; 95% confidence interval, 0.57-1.76, for > or = 30 grams of alcohol/day versus none). The associations did not change with analyses examining different latency periods for coffee and alcohol. Similarly, no statistically significant associations were observed for intakes of tea, decaffeinated coffee, total caffeine, or alcoholic beverages. Data from these two large cohorts do not support any overall association between coffee intake or alcohol intake and risk of pancreatic cancer.

科研通智能强力驱动
Strongly Powered by AbleSci AI

祝大家在新的一年里科研腾飞
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
刚刚
SciGPT应助哈哈哈采纳,获得10
1秒前
诶嘿嘿完成签到,获得积分10
2秒前
炜wei发布了新的文献求助10
2秒前
3秒前
3秒前
ZQJ发布了新的文献求助10
3秒前
lu完成签到,获得积分10
4秒前
4秒前
lyy完成签到 ,获得积分10
6秒前
福明明发布了新的文献求助10
7秒前
7秒前
标致绮露发布了新的文献求助10
8秒前
8秒前
8秒前
9秒前
LYL2003发布了新的文献求助10
9秒前
BOSLobster发布了新的文献求助10
9秒前
舒适不平完成签到,获得积分10
9秒前
情怀应助科研通管家采纳,获得10
10秒前
完美世界应助科研通管家采纳,获得30
10秒前
Ava应助科研通管家采纳,获得10
10秒前
白夜应助科研通管家采纳,获得20
10秒前
深情安青应助科研通管家采纳,获得10
10秒前
小宋应助科研通管家采纳,获得10
10秒前
王立伟发布了新的文献求助10
10秒前
10秒前
打打应助科研通管家采纳,获得10
10秒前
10秒前
10秒前
Hello应助ZQJ采纳,获得10
11秒前
安然僧应助乂则断采纳,获得10
12秒前
奋斗的鱼发布了新的文献求助10
12秒前
大模型应助《子非鱼》采纳,获得10
12秒前
12秒前
今后应助魔幻小蘑菇采纳,获得10
14秒前
14秒前
wendy发布了新的文献求助10
14秒前
轻松盼望发布了新的文献求助10
15秒前
高分求助中
Востребованный временем 2500
The Three Stars Each: The Astrolabes and Related Texts 1500
Classics in Total Synthesis IV: New Targets, Strategies, Methods 1000
Les Mantodea de Guyane 800
Mantids of the euro-mediterranean area 700
The Oxford Handbook of Educational Psychology 600
有EBL数据库的大佬进 Matrix Mathematics 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 内科学 物理 纳米技术 计算机科学 遗传学 化学工程 基因 复合材料 免疫学 物理化学 细胞生物学 催化作用 病理
热门帖子
关注 科研通微信公众号,转发送积分 3412462
求助须知:如何正确求助?哪些是违规求助? 3015168
关于积分的说明 8868829
捐赠科研通 2702831
什么是DOI,文献DOI怎么找? 1481897
科研通“疑难数据库(出版商)”最低求助积分说明 685084
邀请新用户注册赠送积分活动 679733