Synthesis of Five- and Six-Membered-Ring Compounds by Environmentally Friendly Radical Cyclizations Using Kolbe Electrolysis

Substituted carbocycles, tetrahydrofurans, and tetrahydropyrans can be efficiently obtained from ω-unsaturated carboxylic acids. Our methodology involves a Kolbe decarboxylation followed by an intramolecular radical cyclization and a radical-­radical cross-coupling process.