蛋白激酶B
磷酸化
AKT1型
原癌基因蛋白质c-akt
细胞生物学
Pleckstrin同源结构域
PI3K/AKT/mTOR通路
磷脂酰肌醇
化学
生物
信号转导
癌症研究
作者
Nagalingam R. Sundaresan,Vinodkumar B. Pillai,Don Wolfgeher,Sadhana Samant,Prabhakaran Vasudevan,Vishwas Parekh,H. Raghuraman,John M. Cunningham,Madhu Gupta,Mahesh P. Gupta
出处
期刊:Science Signaling
[American Association for the Advancement of Science (AAAS)]
日期:2011-07-19
卷期号:4 (182)
被引量:320
标识
DOI:10.1126/scisignal.2001465
摘要
Deacetylation of Akt and its activating kinase PDK1 promotes cell growth in physiological and pathological settings.
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