亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Influence of Sedation on the Detection Rate of Early Cancer and Precancerous Lesions During Diagnostic Upper Gastrointestinal Endoscopies: A Multicenter Retrospective Study

医学 上皮内瘤变 内窥镜检查 内科学 镇静 癌症 胃肠病学 外科 前列腺
作者
Jiawei Zhou,Zhen Li,Rui Ji,Peizhu Wang,Aijun Zhang,Kangkang Wu,Chengxia Liu,Qiong Niu,Yanliu Chu,Xiufeng Su,Xiuli Zuo,Yanqing Li
出处
期刊:The American Journal of Gastroenterology [Lippincott Williams & Wilkins]
卷期号:116 (6): 1230-1237 被引量:22
标识
DOI:10.14309/ajg.0000000000001201
摘要

INTRODUCTION: The influence of sedation on the endoscopic detection rate of upper gastrointestinal (UGI) early cancer (EC) and precancerous lesions, including high-grade intraepithelial neoplasia (HGIN) and low-grade intraepithelial neoplasia, has not been assessed. The aim of this research is to assess whether the use of sedation can help improve the detection rate of UGI EC and precancerous lesions. The second objective is to evaluate its potential influencing factors. METHODS: The study includes 432,202 patients from a multicenter database from January 2012 to July 2019. Information on endoscopic findings and histology biopsies was obtained from endoscopy quality-control system. Associations of sedation with the detection rate of EC and precancerous lesions were assessed. RESULTS: The sedation group has a higher detection rate of UGI EC and HGIN compared with the no-sedation group, whereas the detection rate of low-grade intraepithelial neoplasia was similar between the 2 groups. There were more cases examined by using staining, image enhancement, or magnifying techniques in the sedation group ( P < 0.001). And, the mean observation time was also longer in the sedation group ( P < 0.001). The type 0-IIb esophageal HGIN and EC cases were significantly increased in the sedation group. No significant difference was detected on lesion subtypes for gastric HGIN and EC according to the Paris classification. More gastric HGIN and EC were detected at gastric body in the sedation group ( P = 0.001). JOURNAL/ajgast/04.03/00000434-202106000-00022/inline-graphic1/v/2023-07-18T070803Z/r/image-tiff DISCUSSION: Sedation may improve the endoscopic detection rate of EC and HGIN in the UGI tract probably through enhancing the use of accessary endoscopic techniques, prolonging observation time, and taking more biopsies in different locations (see Visual Abstract, Supplementary Digital Content 2, http://links.lww.com/AJG/B926).
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
lan发布了新的文献求助10
3秒前
4秒前
一杆长空完成签到,获得积分10
6秒前
热情的未来完成签到,获得积分20
12秒前
义气的蝴蝶完成签到,获得积分10
13秒前
14秒前
临水思长完成签到,获得积分10
15秒前
Lyuhng+1完成签到 ,获得积分10
16秒前
jyy应助薄红采纳,获得10
29秒前
30秒前
量子星尘发布了新的文献求助10
32秒前
kdjm688发布了新的文献求助10
37秒前
科研通AI2S应助cos采纳,获得10
40秒前
FashionBoy应助cos采纳,获得10
40秒前
多情的忆之完成签到,获得积分10
51秒前
pamper完成签到 ,获得积分10
51秒前
52秒前
58秒前
零度完成签到 ,获得积分10
1分钟前
kdjm688发布了新的文献求助10
1分钟前
超级微笑完成签到 ,获得积分10
1分钟前
1分钟前
领导范儿应助完美的流沙采纳,获得10
1分钟前
酷酷的枕头完成签到,获得积分10
1分钟前
刘明坤完成签到 ,获得积分10
1分钟前
SMULJL发布了新的文献求助10
1分钟前
带虾的烧麦完成签到,获得积分10
1分钟前
kdjm688发布了新的文献求助30
1分钟前
克姑美完成签到 ,获得积分10
1分钟前
CipherSage应助杜本内采纳,获得10
1分钟前
123完成签到,获得积分10
1分钟前
SMULJL完成签到,获得积分10
1分钟前
1分钟前
123发布了新的文献求助30
1分钟前
嗯哼哈哈完成签到 ,获得积分10
1分钟前
1分钟前
纯情的无色完成签到 ,获得积分10
1分钟前
1分钟前
1分钟前
1分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976608
求助须知:如何正确求助?哪些是违规求助? 3520700
关于积分的说明 11204542
捐赠科研通 3257350
什么是DOI,文献DOI怎么找? 1798716
邀请新用户注册赠送积分活动 877881
科研通“疑难数据库(出版商)”最低求助积分说明 806613