凝血酶
化学
自溶(生物学)
酶
酯酶
试剂
酶分析
非竞争性抑制剂
水解
色谱法
生物化学
非竞争性抑制
有机化学
血小板
生物
免疫学
作者
L. P. Shvachko,Kibirev Vk
出处
期刊:PubMed
日期:1988-05-01
卷期号:60 (3): 15-9
被引量:1
摘要
Isopropanol is shown to affect considerably the thrombin activity. Its low concentrations (5-15%) activate the hydrolysis reaction of benzoyl-1-arginine ethyl ester (BAEE) by thrombin, whereas incomplete uncompetitive inhibition of the enzyme is observed in the presence of 20% isopropanol. Alcohol in the concentration of 25% results in complete reversible inhibition of the clothing and esterase activity of the enzyme. Isopropanol in the concentration of 25% is able to suppress the thrombin autolysis and therefore it may be used as a reagent which stabilizes thrombin during its storage in the aquatic-salt solutions.
科研通智能强力驱动
Strongly Powered by AbleSci AI