What do scaffold proteins really do

The role of scaffold proteins within signal transduction pathways is an area of current active investigation by biochemists. Much of their effort is presently directed towards identifying which of the many proteins implicated in such pathways, play this role. Moreover the full biological significance of the role is yet to be fully understood. It seems that generic models of the dynamic properties of scaffold proteins and their influence on the signalling can be helpful in interpreting experimental data and developing understanding. We have been developing some PEPA models of the role of scaffold proteins. In this paper we report the results of our preliminary experiments.