超声波
分子成像
医学
软件可移植性
医学物理学
超声成像
放射科
计算机科学
生物
生物技术
程序设计语言
体内
作者
Vishal D. Thumar,MD Ji-Bin Liu,PhD John R. Eisenbrey
标识
DOI:10.37015/audt.2019.190812
摘要
Molecular ultrasound imaging or targeted contrast-enhanced ultrasound (CEUS) is a relatively new technique that has varied applications to augment both diagnostics and therapeutics.Ultrasound contrast agents are conjugated to ligands that bind with specific biomarkers in the areas of interest which can then be quantified using ultrasound technology.This technique has numerous clinical applications including studying pathophysiology of disease, improving diagnostic sensitivity and specificity, and improving localized drug delivery.This technology, most notably, has proven useful in numerous oncologic and cardiovascular applications.Given ultrasound's advantages over other radiographic studies including its low cost, lack of ionizing radiation, portability, ability to provide real-time imaging, and non-invasiveness, recent investigations have expanded the utility of molecular ultrasound.In this review, we briefly review targeted ultrasound contrast agents and explore the current applications of molecular ultrasound as well as future applications based on the currently published literature.
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