药代动力学
分子成像
药品
正电子发射断层摄影术
药物作用
药理学
分布(数学)
组织分布
医学
体内
医学物理学
核医学
生物
内科学
数学分析
生物技术
数学
作者
Xinping Li,Yan Wang,Guo Lu,Yanjing Li,Xue Yu,Wei Hou,Changxiao Liu
出处
期刊:Int J Radiat Med Nucl Med
日期:2019-07-25
卷期号:43 (4): 349-355
标识
DOI:10.3760/cma.j.issn.1673-4114.2019.04.009
摘要
Pharmacokinetics is an important part of pharmacology, which is guide for drug using rationally, preventing adverse reactions, studying the mechanism of action and drug-drug interaction. PET molecular imaging technology is able to dynamically monitor physiological, biochemical and biological processes in vivo, and it can be applied to the study of pharmacokinetics, tissues distribution and drug-drug interaction. All of these will promote new drug development. This paper summarizes the applications of PET molecular imaging technology to pharmacokinetics in recent years.
Key words:
Positron emission tomography; Molecular imaging; Pharmacokinetics; Tissue distribution; Drug interactions
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