材料科学
氮化硼
铁氧体(磁铁)
纳米颗粒
透射电子显微镜
纳米技术
磁性纳米粒子
硼
化学工程
化学
复合材料
工程类
有机化学
作者
Thaylice CS Cabral,José D. Ardisson,Marcelo Coutinho de Miranda,Dawidson Assis Gomes,L.E. Fernández-Outón,E. M. B. Sousa,Tiago Hilário Ferreira
出处
期刊:Nanomedicine
[Future Medicine]
日期:2019-12-01
卷期号:14 (23): 3075-3088
被引量:4
标识
DOI:10.2217/nnm-2019-0123
摘要
Aim: The field of nanotechnology promotes the development of innovative and more effective cancer therapies. This work is aimed to develop a hybrid system that combines the capacity of boron nitride nanotubes (BNNTs) to be internalized by tumor cells and the ability of nickel ferrite nanoparticles to efficiently release heat by induced AC magnetic heating. Materials & methods: The systems studied were characterized by using x-ray diffractometry, transmission electron microscopy, vibrating sample magnetometry and Mössbauer spectroscopy. Results: The ferrite nanoparticles attached to BNNT were able to achieve the required temperatures for magnetohyperthermia therapies. After cellular internalization, AC induced magnetic heating of BNNT@NiFe2O4 can kill almost 80% of Hela cells lineage in a single cycle. Conclusion: This system can be a highly efficient magnetohyperthermia agent in cancer therapy.
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