Mechanistic insights for the transprotection of tertiary amines with Boc2O via charged carbamates: access to both enantiomers of 2-azanorbornane-3-exo-carboxylic acids

Development of a synthetic methodology for the selective transprotection in hindered tertiary amines using Boc₂O under N–C hydrogenolysis catalyzed by Pd/C: access to both enantiomers of 2-azanorbornane-3-exo-carboxylates.