相关性
计算机科学
代表(政治)
比例(比率)
计算生物学
复杂疾病
嵌入
机器学习
数据挖掘
人工智能
基因
生物
遗传学
数学
几何学
政治
物理
量子力学
法学
政治学
作者
Yang Liu,Yuchen Guo,Xiaoyan Liu,Chuyu Wang,Maozu Guo
摘要
In disease research, the study of gene-disease correlation has always been an important topic. With the emergence of large-scale connected data sets in biology, we use known correlations between the entities, which may be from different sets, to build a biological heterogeneous network and propose a new network embedded representation algorithm to calculate the correlation between disease and genes, using the correlation score to predict pathogenic genes. Then, we conduct several experiments to compare our method to other state-of-the-art methods. The results reveal that our method achieves better performance than the traditional methods.
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