Synthesis and Molecular Modeling Studies of Novel 2,4-Disubstituted-1, 5-Diphenyl-1-H-Imidazole Derivatives as Potential Anti-Tubercular Agents

Background: The present discussion reports the synthesis of a series of novel derivatives 2, 4-disubstituted -1, 5 -diphenyl substituted -1-H-imidazole derivatives and their molecular modeling studies as antitubercular agents. Keywords: Imidazole, schiffs base, TOSMIC, antitubercular, QSAR, pharmacophore, Microplate Alamar Blue Assay.