Role of MDCT in the detection of early abdominal complications after orthotopic liver transplantation

Abstract

Purpose

This study aims to assess the role of multidetector computed tomography (MDCT) for detecting early abdominal complications after orthotopic liver transplantation.

Materials and methods

We retrospectively enrolled 170 subjects with clinical laboratory and/or echo-color Doppler abnormalities who underwent MDCT within the first 90 days after transplantation. All images were reviewed by two radiologists in conference and imaging results were correlated with digital subtraction angiography, conventional cholangiography, surgery, clinical laboratory, and/or imaging follow-up.

Results

No significant complication was found in 142 patients, while vascular complications (hepatic artery thrombosis, n=5 and stenosis, n=5; portal vein thrombosis, n=4; cava vein thrombosis, n=1; arterial bleeding, n=1), biliary complications (anastomotic leak with biloma, n=6), parenchymal complications (abscess, n=1; extended areas of impaired perfusion, n=3), adrenal hemorrhage (n=1), and bowel perforation (n=1) were identified in the remaining 28 cases. Four false-positive cases (three hepatic artery stenoses and one hepatic artery dissection) and one false-negative case (biloma) were diagnosed on MDCT. The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of MDCT in the identification of various complications were 96%, 97%, 87%, 99%, and 97%, respectively.

Conclusion

MDCT is a reliable diagnostic technique in the identification of early abdominal complications of liver recipients.